SDF-1 alpha (CXCL12)
Stromal cell-derived factor (SDF) -1 alpha and SDF-1 beta are the first cytokines initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. They are encoded by a single gene, PBSF, and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 beta and absent from SDF-1 alpha. SDF-1/PBSF is highly conserved between species. Human mature SDF-1 shares approximately 99% amino acid sequence identity with the mouse protein.
Product Specifications
Synonyms
Cxcl12; Sdf1
NCBI Gene ID
24772
UniProt
Q9QZD1
Accession Number
NP_071513.1
Accession Number mRNA
NM_022177.3
Chromosomal Location
4q42.1
Reactivity
Rat
Cross Reactivity
Human
Sequence
KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml.
Length
68
Form
Lyophilized
Molecular Weight
7.9 kDa
Host or Source
E. coli
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
HDAC11 (Histone Deacetylase 11, HD11, HD-11, FLJ22237) (Biotin) discontinued
P/P003/NL62/RFLBD-600X400-1 Facility & Office Signs (No Adhesive)