Relaxin-2
Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.
Product Specifications
Synonyms
H2 relaxin, RLN2
NCBI Gene ID
6019
UniProt
P04090
Accession Number
NP_005050.2
Accession Number mRNA
NM_005059.3
Reactivity
Human
Cross Reactivity
Human
Sequence
A-Chain: QLYSALANKC CHVGCTKRSL ARFC; B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Data not available.
Length
53
Form
Lyophilized
Molecular Weight
6.0 kDa
Host or Source
E. coli
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
XRCC4 (X-ray Repair Cross-complementing Protein 4, DNA Repair Protein XRCC4) (AP) discontinued
Olr1868 sgRNA CRISPR Lentivector (Rat) (Target 2)