RANTES (CCL 5)

RANTES is a protein which has been shown to be a chemoattractant for peripheral blood monocytes. It appears to selectively attract T cells of the CD4+/CD45RO+ phenotype in vitro. Recombinant Rat RANTES is a 7.9 kDa protein containing 68 amino acid residues.

Product Specifications

Synonyms

Ccl5; Scya5; Rantes

NCBI Gene ID

81780

UniProt

P50231

Accession Number

AAA96499

Accession Number mRNA

U06436

Chromosomal Location

10q26

Reactivity

Rat

Cross Reactivity

Human, Mouse, Rat

Sequence

SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Assay#1: Determined by its ability to chemoattract rat peritoneal macrophages using a concentration range of 50.0-100.0 ng/ml. Assay#2: Determined by its ability to chemoattract human blood monocytes using a concentration range of 10.0-100.0 ng/ml.