Prolactin / PRL Protein (His Tag)
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial cells (astrocytes, microglia and oligodendrocytes) of the brain. It is generally believed that in vertebrates, prolactin (PRL) is predominantly synthesized and released by pituitary lactotrophs and plays important roles in many physiological processes via activation of PRL receptor (PRLR), including water and electrolyte balance, reproduction, growth and development, metabolism, immuno-modulation, and behavior.
Product Specifications
Synonyms
Gha1 Protein; Prl Protein; Prl1a1 Protein
Accession Number
NP_035294.2
Reactivity
Human
Cross Reactivity
Mouse
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 92 % as determined by SDS-PAGE.≥ 90 % as determined by SEC-HPLC.
Bioactivity
Measured by its ability to induce PRL pathway activation in a Luciferase receptor Assay System. The ED50 for this effect is typically 50-500 ng/mL.
Length
207
Form
Lyophilized or frozen liquid
Buffer
21 mM Tris, 300 mM NaCl, 10% Glycerol, pH 7.5.
Reconstitution
See Datasheet
Molecular Weight
26 kDa
Storage Conditions
Host or Source
Insect cells
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