Prolactin
Prolactin, also known as mammotrophin, luterotropic hormone, and lutetropin, is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant human Prolactin is a 23 kDa globular protein containing 200 amino acid residues.
Product Specifications
Synonyms
Mammotropin, Luterotropic hormone, Lutetropin
NCBI Gene ID
5617
UniProt
P01236
Accession Number
NP_000939.1
Accession Number mRNA
NM_000948
Chromosomal Location
6p22.2-p21.3
Reactivity
Human
Cross Reactivity
Rat, Human
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.
Length
200
Form
Lyophilized
Molecular Weight
23 kDa
Host or Source
E. coli
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