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PRL / Prolactin Protein (His Tag)

Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial cells (astrocytes, microglia and oligodendrocytes) of the brain. It is generally believed that in vertebrates, prolactin (PRL) is predominantly synthesized and released by pituitary lactotrophs and plays important roles in many physiological processes via activation of PRL receptor (PRLR), including water and electrolyte balance, reproduction, growth and development, metabolism, immuno-modulation, and behavior.

Product Specifications

Synonyms

Gha1 Protein; Prl Protein; Prl1a1 Protein

Accession Number

NP_035294.2

Reactivity

Mouse

Cross Reactivity

Mouse

Label

His-Tag

Assay Protocol

See Datasheet send with the product

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 92 % as determined by SDS-PAGE.≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to induce PRL pathway activation in a Luciferase receptor Assay System. The ED50 for this effect is typically 50-500 ng/mL.

Length

207

Form

Lyophilized

Buffer

20 mM Tris, 300 mM NaCl, 10% Glycerol, pH 7.5.

Reconstitution

See Datasheet

Molecular Weight

26 kDa

Storage Conditions

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Host or Source

Insect cells

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