MIP-3 alpha (CCL20)
MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 alpha is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20; MIP-3-alpha
NCBI Gene ID
6363
UniProt
P78556
Accession Number
NP_004582.1
Accession Number mRNA
NM_004591
Chromosomal Location
9p13
Reactivity
Human
Cross Reactivity
Mouse, Rat, Human
Sequence
ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.
Length
70
Form
Lyophilized
Molecular Weight
8.0 kDa
Host or Source
E. coli
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
RPN1 (ribophorin I, DKFZp686B16177, OST1, RBPH1) (FITC)
RPN1 (ribophorin I, DKFZp686B16177, OST1, RBPH1) (FITC)
