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MIP-1 gamma (CCL9/10)

MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.

Product Specifications

Synonyms

Ccl9; CCF18; MRP-2; Scya9; Scya10

NCBI Gene ID

20308

UniProt

P51670

Accession Number

NP_035468.1

Accession Number mRNA

NM_011338.2

Chromosomal Location

11 C; 11 47.4 cM

Reactivity

Mouse

Cross Reactivity

Human

Sequence

QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.

Length

101

Form

Lyophilized

Molecular Weight

11.6 kDa

Host or Source

E. coli

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