MIA-2 (Melanoma inhibitory activity 2)
MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3) -like domain. MIA2 is predominantly expressed in hepatocytes. Elevated levels of MIA2 may represent a clinically useful marker for diagnosis of hepatic disease activity and severity. Recombinant human MIA-2 is a 101 amino acid, 11.5 kDa protein comprising the MIA homologous N-terminal region of the full length MIA-2 protein.
Product Specifications
Synonyms
MIA2
NCBI Gene ID
117153
UniProt
Q96PC5
Accession Number
NP_473365
Accession Number mRNA
NM_054024
Chromosomal Location
14q13.2
Reactivity
Human
Cross Reactivity
Human
Sequence
MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Data not available.
Length
101
Form
Lyophilized
Molecular Weight
11.5 kDa
Host or Source
E. coli
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