What is the catalog number for Mesothelin Protein (His Tag)?

The catalog number for Mesothelin Protein (His Tag) is M60-133-L100.

What sizes are available for Mesothelin Protein (His Tag)?

Mesothelin Protein (His Tag) is available in the following size(s): 100 µg.

Is Mesothelin Protein (His Tag) in stock?

Mesothelin Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Mesothelin Protein (His Tag)?

Mesothelin Protein (His Tag) is requires dry ice shipping.

Mesothelin Protein (His Tag)

The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level) . It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.

Product Specifications

Synonyms

Mes Protein; MPF Protein; Msln Protein

Accession Number

Q61468-1

Reactivity

Mouse

Cross Reactivity

Mouse

Label

His-Tag

Assay Protocol

See Datasheet send with the product

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Loaded anti-human MSLN antibody, IgG1 on ProA Biosensor, can bind Recombinant Mouse Mesothelin Protein, His Tag with an affinity constant of 0.14 μM as determined in BLI assay (Sartorius Octet RED384) .

Length

314

Form

Lyophilized

Buffer

PBS, pH 7.4

Reconstitution

See Datasheet

Molecular Weight

44 kDa

Storage Conditions

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.