Lymphotactin
Lymphotactin is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes but not towards monocytes or neutrophils. Recombinant human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues.
Product Specifications
Synonyms
XCL1; LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
NCBI Gene ID
6375
UniProt
P47992
Accession Number
NP_002986.1
Accession Number mRNA
NM_002995
Chromosomal Location
1q23
Reactivity
Human
Cross Reactivity
Mouse, Human, Hamster, Bacteria
Sequence
GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human T cells using a concentration of 10.0-100.0 ng/ml.
Length
92
Form
Lyophilized
Molecular Weight
10 kDa
Host or Source
E. coli
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