LIGHT (Animal Free)
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to activate NF-κB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant Murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues, comprising the TNF-homologous region of the LIGHT extracellular domain.
Product Specifications
Synonyms
Tnfsf14; LTg; HVEML; LIGHT; Ly113; HVEM-L; LIGHT; tumor necrosis factor (ligand) superfamily, member 14
NCBI Gene ID
50930
UniProt
Q9QYH9
Accession Number
NP_062291
Accession Number mRNA
NM_019418
Chromosomal Location
17; 17 D-E1
Reactivity
Mouse
Cross Reactivity
Human, Mouse
Sequence
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Not available.
Length
183
Form
Lyophilized
Molecular Weight
20.1 kDa
Host or Source
E. coli
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Chromatography Packing Adsorbents, Silica,40-63um,60A, irregular,200g/pk
RBM18 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
GC1qR, ID (Complement Component 1 Q Subcomponent-binding Protein Mitochondrial, Glycoprotein gC1qBP, C1qBP, GC1q-R Protein, GC1QBP, Hyaluronan-binding Protein 1, HABP1, Mitochondrial Matrix Protein p32, p33, SF2P32) (MaxLight 550)