I-TAC (CXCL11) (Animal Free)
I-TAC is a 'non-ELR' CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, ormonocytes. Recombinant Human I-TAC (CXCL11) is an 8.3 kDa protein containing 73 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.
Product Specifications
Synonyms
CXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B
NCBI Gene ID
6373
UniProt
O14625
Accession Number
NP_005400.1
Accession Number mRNA
NM_005409.4
Chromosomal Location
4q21.2
Reactivity
Human
Cross Reactivity
Hamster, Mouse, Rabbit, Human, Monkey
Sequence
FPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Determined by its ability to chemoattract human T-cells activated with IL-2.
Length
73
Form
Lyophilized
Molecular Weight
8.3 kDa
Host or Source
E. coli
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