IP-10 (CXCL10)
Murine IP-10 is produced by several cell types during the delayed type hypersensitivity response. IP-10 acts as a chemoattractant towards monocytes, lymphocytes, and certain T cells. Recombinant Murine IP-10 is a 8.7 kDa protein, containing 77 amino acid residues.
Product Specifications
Synonyms
Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
NCBI Gene ID
15945
UniProt
P17515
Accession Number
NP_067249.1
Accession Number mRNA
NM_021274.2
Chromosomal Location
5 E2; 5 53.0 cM
Reactivity
Mouse
Cross Reactivity
Human, Mouse, Rat, Monkey
Sequence
IPLARTVRCNCIHIDDGPVRMRAIGKLEIIPASLSCPRVEIIATMKKNDEQRCLNPESKTIKNLMKAFSQKRSKRAP
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Assay #1: Determined by its ability to chemoattract IL-2 activated T cells using a concentration range of 0.1-10.0 ng/ml. Assay #2: Determined by its ability to chemoattract CXCR3 transfected/HEK293 cells using a concentration range of 100-500 ng/ml.
Length
77
Form
Lyophilized
Molecular Weight
8.7 kDa
Host or Source
E. coli
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