IL-9
IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease. Recombinant rat IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.
Product Specifications
Synonyms
Il19
NCBI Gene ID
116558
UniProt
D4A819
Accession Number
NP_001099217
Accession Number mRNA
NM_001105747
Chromosomal Location
17p14
Reactivity
Rat
Cross Reactivity
Human
Sequence
MQRCSTSWGI QHTSYLIENL KDDPSSKCSC SANVTSCLCL PIPSDDCTTP CFQEGMSQVT NATQQSKFSP FFFRVKRIVE TLKSNKCQFF SCEKPCNQTT AGNTVSFLKS LLKTFQKTEV QVQRSRA
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Measured by its ability to enhance MC/9 cell proliferation.
Length
127
Form
Lyophilized
Molecular Weight
14.3 kDa
Host or Source
E. coli
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