IL-28B
IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA) .
Product Specifications
Synonyms
Interferon lambda-3, IFN-lambda-3, Interleukin-28B, IL-28B, Ifnl3, Il28, Il28b
NCBI Gene ID
338374
UniProt
Q8CGK6
Accession Number
NP_796370.1
Accession Number mRNA
NM_177396.1
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
Assay Protocol
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 97% by SDS-PAGE & HPLC analyses
Bioactivity
Length
174
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Molecular Weight
19.6 kDa
Storage Conditions
Lyophilized IL-28B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.
Host or Source
E. coli
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