IGFBP5 / IGFBP-5 Protein (His Tag)
Enables insulin-like growth factor I binding activity and receptor ligand activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis. [provided by Alliance of Genome Resources, Jun 2025]
Product Specifications
Synonyms
IBP5 Protein
Accession Number
NP_000590.1
Reactivity
Human
Cross Reactivity
Human
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE.
Bioactivity
Measured by its ability to inhibit the biological activity of IGFI or IGFII on MCF7 human breast cancer cells. The ED50 for this effect is 0.1-0.5μg/mL in the presence of 14 ng/mL rhIGFII.
Length
263
Form
Lyophilized
Buffer
20 mM Tris, pH 8.0, 300 mM NaCl, 10 % glycerol.
Reconstitution
See Datasheet
Molecular Weight
30 kDa
Storage Conditions
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Host or Source
Insect cells
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