IFNL2 / IL28A Protein (His Tag)
Recombinant human Interferon-lambda2 (IFN-?2) is a 19.6 kDa protein containing 174 amino acid residues. IFN-lambda-1, -2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14) . Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.
Product Specifications
Synonyms
EG330496 Protein; If1ia1 Protein; Ifnl2 Protein; IL-28A Protein; Il28a Protein
Accession Number
NP_001019844.2
Reactivity
Mouse
Cross Reactivity
Mouse
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Measured in antiviral assay using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 1-4 ng/mL.
Length
185
Form
Lyophilized or frozen liquid
Buffer
PBS, pH 7.4
Reconstitution
See Datasheet
Molecular Weight
28.5 kDa (glycosylated)
Storage Conditions
Host or Source
HEK 293 cells
Frequently Asked Questions
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