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GRO-beta/MIP-2

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Product Specifications

Synonyms

Cxcl2; Mip-2; Scyb2

NCBI Gene ID

114105

UniProt

P30348

Accession Number

NP_446099

Accession Number mRNA

NM_053647

Chromosomal Location

14p22

Reactivity

Rat

Cross Reactivity

Human, Mouse, Rat

Sequence

VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.

Length

73

Form

Lyophilized

Molecular Weight

7.9 kDa

Host or Source

E. coli

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