GRO-beta (CXCL2)
Human GROß is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. GROß like GROa specifically inhibits growth factor-stimulated proliferation of capillary endothelial cells in a dose-dependent manner. Human GROß is a 7.9 kDa protein containing 73 amino acid residues.
Product Specifications
Synonyms
CXCL2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
NCBI Gene ID
2920
UniProt
P19875
Accession Number
NP_002080.1
Accession Number mRNA
NM_002089.3
Chromosomal Location
4q21
Reactivity
Human
Cross Reactivity
Hamster, Human, Mouse
Sequence
APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.
Length
73
Form
Lyophilized
Molecular Weight
7.9 kDa
Host or Source
E. coli
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