GRO-alpha/MGSA (CXCL1)

Human GRO alpha (also known as MGSA) promotes neutrophil chemotaxis and degranulation. It also stimulates mitogenesis in certain human melanoma cells. Human GROa is a 7.8 kDa protein containing 73 amino acid residues

Product Specifications

Synonyms

CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a

NCBI Gene ID

2919

UniProt

P03941

Accession Number

NP_001502.1

Accession Number mRNA

NM_001511.3

Chromosomal Location

4q21

Reactivity

Human

Cross Reactivity

Hamster, Monkey, Mouse, Rat, Human

Sequence

ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.

Length

Form

Lyophilized

Molecular Weight

7.8 kDa

Host or Source

E. coli

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