GRO/KC (CXCL1)
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Product Specifications
Synonyms
Cxcl1; Gro1; CINC-1
NCBI Gene ID
81503
UniProt
P14095
Accession Number
NP_110472.1
Accession Number mRNA
NM_030845.1
Chromosomal Location
14p22
Reactivity
Rat
Cross Reactivity
Rat, Mouse
Sequence
APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.
Length
72
Form
Lyophilized
Molecular Weight
7.8 kDa
Host or Source
E. coli
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