GCP-2 (CXCL6)
GCP-2 is a connective tissue derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. GCP-2 selectively attracts neutrophils and has also been shown to exert anti-angiogenic activity. Human GCP-2 is cross-react on murine cells. Recombinant human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues.
Product Specifications
Synonyms
CXCL6; GCP2; CKA-3; GCP-2; SCYB6
NCBI Gene ID
6372
UniProt
P80163
Accession Number
NP_002984.2
Accession Number mRNA
NM_002993.4
Chromosomal Location
4q21
Reactivity
Human
Cross Reactivity
Hamster, Monkey, Rat, Human, Bacteria
Sequence
VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.
Length
72
Form
Lyophilized
Molecular Weight
7.9 kDa
Host or Source
E. coli
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