Galectin 3 / LGALS3 Protein (His Tag)
LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA) . Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
Product Specifications
Synonyms
CBP35 Protein; GAL3 Protein; GALBP Protein; GALIG Protein; L31 Protein; LGALS2 Protein; MAC-2 Protein; MAC2 Protein
Accession Number
NP_002297.2
Reactivity
Human
Cross Reactivity
Human
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
Data not available
Length
260
Form
Lyophilized or frozen liquid
Buffer
PBS, 2 mM Tcep, pH 6.5.
Reconstitution
See Datasheet
Molecular Weight
34.9 kDa
Storage Conditions
Host or Source
HEK 293 cells
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