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Fractalkine (CX3CL1)

Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Recombinant human Fractalkine is an 8.5 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Product Specifications

Synonyms

CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin

NCBI Gene ID

6376

UniProt

P78423

Accession Number

NP_002987.1

Accession Number mRNA

NM_002996.3

Chromosomal Location

16q13

Reactivity

Human

Cross Reactivity

Monkey, Mouse, Rat, Human, Bacteria

Sequence

QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract human T cells using a concentration range of 5.0-10.0 ng/ml.

Length

76

Form

Lyophilized

Molecular Weight

8.5 kDa

Host or Source

E. coli

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