FGF-8a
FGF-8 is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8a, FGF-8b, FGF-8e and FGF-8f. The human and murine FGF-8a and FGF-8b are identical, unlike human and mouse FGF-8e and FGF-8f, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. CHO cell-derived recombinant human FGF-8a is a 21.2 kDa protein consisting of 182 amino acid residues.
Product Specifications
Synonyms
Fibroblast Growth Factor-8, FGF-8a, AIGF, HBGF-8
NCBI Gene ID
2253
UniProt
P55075-2
Accession Number
NP_149355.1
Accession Number mRNA
NM_033165.3
Reactivity
Human
Cross Reactivity
Human
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by a cell proliferation assay using balb/c 3T3 cells.
Length
182
Form
Lyophilized
Molecular Weight
21.2 kDa
Host or Source
CHO cells
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