What is the catalog number for FGF21 Protein (His Tag)?

The catalog number for FGF21 Protein (His Tag) is 600-117-L50.

What sizes are available for FGF21 Protein (His Tag)?

FGF21 Protein (His Tag) is available in the following size(s): 50 µg.

Is FGF21 Protein (His Tag) in stock?

FGF21 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for FGF21 Protein (His Tag)?

FGF21 Protein (His Tag) is requires dry ice shipping.

FGF21 Protein (His Tag)

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

Product Specifications

Synonyms

Fgf21 Protein; Fgf8c Protein; UNQ3115/PRO10196 Protein

Accession Number

NP_061986.1

Reactivity

Human

Cross Reactivity

Human

Label

His-Tag

Assay Protocol

See Datasheet send with the product

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.1-1 µg/mL in the presence of 2.5 µg/mL of rm Klotho β.

Length

188

Form

Lyophilized

Buffer

50 mM Tris, 10 % glycerol, 0.05 % Brij 35, pH 8.0

Reconstitution

See Datasheet

Molecular Weight

23 kDa

Storage Conditions

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.