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FGF-19

The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high affinity heparin dependent ligand for FGFR4. FGF-19 is expressed during the brain development and embryogenesis. Recombinant human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.

Product Specifications

Synonyms

FGF19

NCBI Gene ID

9965

UniProt

O95750

Accession Number

NP_005108.1

Accession Number mRNA

NM_005117

Chromosomal Location

11q13.1

Reactivity

Human

Cross Reactivity

Mouse, Hamster

Sequence

MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 95% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml.

Length

195

Form

Lyophilized

Molecular Weight

21.8 kDa

Host or Source

E. coli

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