FGF-18
FGF-18 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-18 is an essential regulator of long bone and calvarial development. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. Recombinant E.coli derived human FGF-18 is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from c-terminal truncation of the full length protein.
Product Specifications
Synonyms
FGF18; ZFGF5; FGF-18
NCBI Gene ID
8817
UniProt
O76093
Accession Number
NP_003853.1
Accession Number mRNA
NM_003862
Chromosomal Location
5q34
Reactivity
Human
Cross Reactivity
Mouse, Rat, Human
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
Length
173
Form
Lyophilized
Molecular Weight
20.1 kDa
Host or Source
E. coli
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