FGF-16
FGF-16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant human FGF-16 is a 23.7 kDa protein consisting of 207 amino acid residues.
Product Specifications
Synonyms
FGF16; FGF-16
NCBI Gene ID
8823
UniProt
O43320
Accession Number
NP_003859
Accession Number mRNA
NM_003868
Chromosomal Location
Xq13
Reactivity
Human
Cross Reactivity
Mouse
Sequence
AEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
The biological activity was determined by the FGF-10-induced proliferation of 4MBr-5 cells.
Length
207
Form
Lyophilized
Molecular Weight
23.7 kDa
Host or Source
E. coli
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