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FGF-16

FGF-16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant human FGF-16 is a 23.7 kDa protein consisting of 207 amino acid residues.

Product Specifications

Synonyms

FGF16; FGF-16

NCBI Gene ID

8823

UniProt

O43320

Accession Number

NP_003859

Accession Number mRNA

NM_003868

Chromosomal Location

Xq13

Reactivity

Human

Cross Reactivity

Mouse

Sequence

AEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 95% by SDS-PAGE & HPLC analyses

Bioactivity

The biological activity was determined by the FGF-10-induced proliferation of 4MBr-5 cells.

Length

207

Form

Lyophilized

Molecular Weight

23.7 kDa

Host or Source

E. coli

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