EG-VEGF / prokineticin-1 Protein (His Tag)
EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEGF can be detected in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF has little or no effect on a variety of other endothelial and non-endothelial cell types. It induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. EG-VEGF may play a role in placentation. It may also function in normal and pathological testis angiogenesis. It positively regulates PTGS2 expression and prostaglandin synthesis.
Product Specifications
Synonyms
EG-VEGF Protein; EGVEGF Protein; PK1 Protein; PRK1 Protein; UNQ600/PRO1186 Protein
Accession Number
P58294
Reactivity
Human
Cross Reactivity
Human
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Data not available
Length
96
Form
Lyophilized
Buffer
20mM Tris, 500mM NaCl, pH 7.4, 0.02% Tween-80, 10% gly, 1mM DTT
Reconstitution
See Datasheet
Molecular Weight
15 kDa (glycosylated)
Storage Conditions
Host or Source
Insect cells
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