CTGFL/WISP-2
CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.8 kDa protein of 228 amino acid residues.
Product Specifications
Synonyms
WISP2; CCN5; CT58; CTGF-L
NCBI Gene ID
8839
UniProt
O76076
Accession Number
NP_003872
Accession Number mRNA
NM_003881
Chromosomal Location
20q13.12
Reactivity
Human
Cross Reactivity
Human
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
Length
228
Form
Lyophilized
Molecular Weight
24.3 kDa
Host or Source
E. coli
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