CTACK/ CCL27
CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant human CTACK is a 10.2 kDa protein containing 88 amino acid residues.
Product Specifications
Synonyms
CCL27; ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
NCBI Gene ID
10850
UniProt
Q9Y4X3
Accession Number
NP_006655
Accession Number mRNA
NM_006664
Chromosomal Location
9p13
Reactivity
Human
Cross Reactivity
Mouse, Human, Bacteria
Sequence
FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract CXCR3 transfected cells using a concentration of 10.0-100 ng/ml.
Length
88
Form
Lyophilized
Molecular Weight
10.2 kDa
Host or Source
E. coli
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