CCL2 / MCP-1 / MCP1 Protein (His Tag)

Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.

Product Specifications

Synonyms

Ccl2 Protein; HC11 Protein; JE Protein; MCAF Protein; MCP-1 Protein; MCP1 Protein; Scya2 Protein; Sigje Protein; SMC-CF Protein

Accession Number

NP_035463.1

Reactivity

Mouse

Cross Reactivity

Mouse

Label

His-Tag

Assay Protocol

See Datasheet send with the product

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Data not available

Length

135

Form

Lyophilized

Buffer

20 mM Tris, 500 mM NaCl, 10 % Glycerol, pH 7.4

Reconstitution

See Datasheet send with the product

Molecular Weight

15.2 kDa

Storage Conditions

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.