CCL2 / MCP-1 / MCP1 Protein (His Tag)
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.
Product Specifications
Synonyms
GDCF-2 Protein; HC11 Protein; HSMCR30 Protein; MCAF Protein; MCP-1 Protein; MCP1 Protein; MGC9434 Protein; SCYA2 Protein; SMC-CF Protein
Accession Number
NP_002973.1
Reactivity
Human
Cross Reactivity
Human
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with mouse CCR2. The ED50 for this effect is 20-200 ng/mL.
Length
86
Form
Lyophilized
Buffer
PBS, pH 7.4
Reconstitution
See Datasheet send with the product
Molecular Weight
10.1 kDa
Storage Conditions
Host or Source
Yeast
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
