CCL2 / MCP-1 / MCP1 Protein (His Tag)
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.
Product Specifications
Synonyms
GDCF-2 Protein; HC11 Protein; HSMCR30 Protein; MCAF Protein; MCP-1 Protein; MCP1 Protein; MGC9434 Protein; SCYA2 Protein; SMC-CF Protein
Accession Number
NP_002973.1
Reactivity
Human
Cross Reactivity
Human
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with mouse CCR2. The ED50 for this effect is 20-200 ng/mL.
Length
86
Form
Lyophilized
Buffer
PBS, pH 7.4
Reconstitution
See Datasheet send with the product
Molecular Weight
10.1 kDa
Storage Conditions
Host or Source
Yeast
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