CCL19 / MIP-3b Protein (His Tag)
Chemokine (C-C motif) ligand 19 (CCL19) also known as macrophage inflammatory protein 3β (MIP-3β) belongs to the family of CC-motif chemokines, characterized by four highly conserved cysteine residues. CCL19 is a chemoattractant involved in the regulation of lymphocyte circulation and homing in the thymus and secondary lymphoid organs. It is expressed in thymus and lymph nodes and binds to chemokine receptor CCR7, which is expressed on lymphocytes, such as central memory T cells, and myeloid progenitors. CCL19 is also important for migration of antigen presenting cells, such as dendritic cells and antigen-loaded B cells. Human MIP-3β is active on murine cells.
Product Specifications
Synonyms
Ccl19 Protein; CKb11 Protein; ELC Protein; exodus-3 Protein; Gm2023 Protein; MIP3B Protein; Scya19 Protein
Accession Number
NP_036018.1
Reactivity
Mouse
Cross Reactivity
Mouse
Label
His-Tag
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Data not available
Length
94
Form
Lyophilized
Buffer
20 mM Tris, 300 mM NaCl, 10 % Glycerol, pH 8.0
Reconstitution
See Datasheet send with the product
Molecular Weight
10.7 kDa
Storage Conditions
Host or Source
Insect cells
Frequently Asked Questions
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