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CCL19 / MIP-3b Protein (His Tag)

Chemokine (C-C motif) ligand 19 (CCL19) also known as macrophage inflammatory protein 3β (MIP-3β) belongs to the family of CC-motif chemokines, characterized by four highly conserved cysteine residues. CCL19 is a chemoattractant involved in the regulation of lymphocyte circulation and homing in the thymus and secondary lymphoid organs. It is expressed in thymus and lymph nodes and binds to chemokine receptor CCR7, which is expressed on lymphocytes, such as central memory T cells, and myeloid progenitors. CCL19 is also important for migration of antigen presenting cells, such as dendritic cells and antigen-loaded B cells. Human MIP-3β is active on murine cells.

Product Specifications

Synonyms

Ccl19 Protein; CKb11 Protein; ELC Protein; exodus-3 Protein; Gm2023 Protein; MIP3B Protein; Scya19 Protein

Accession Number

NP_036018.1

Reactivity

Mouse

Cross Reactivity

Mouse

Label

His-Tag

Assay Protocol

See Datasheet send with the product

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Data not available

Length

94

Form

Lyophilized

Buffer

20 mM Tris, 300 mM NaCl, 10 % Glycerol, pH 8.0

Reconstitution

See Datasheet send with the product

Molecular Weight

10.7 kDa

Storage Conditions

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Host or Source

Insect cells

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