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Recombinant Phospho-TBK1/NAK (Ser172) Monoclonal Antibody

Product Specifications

Background

TBK1 (tumor necrosis factor (TNF) receptor-associated factor NF-kB activator (TANK) -binding kinase 1), also named as NF-kB-activating kinase (NAK), T2K, is a multimeric kinase that modulates inflammation and autophagy. It is a ubiquitously expressed serine-threonine kinase belonging to the 'noncanonical IkB kinases' (IKKs) recognized for its critical role in regulating type I IFN production. TBK1 is also an important player in autophagy.

Abbreviation

Phospho-TBK1/NAK (Ser172)

UniProt

Q9UHD2

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Phosphorylated human TBK1/NAK (Ser172) peptide

Target

TBK; FTDALS; TBK1; FTDALS4; NAK; T2K

Clonality

Monoclonal,Recombinant

Clone

A843

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Signal Transduction; Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

84 kDa

Observed Molecular Weight

84 kDa

Isotype

IgG, κ

Available Sizes

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