Recombinant Phospho-TBK1/NAK (Ser172) Monoclonal Antibody
Product Specifications
Background
TBK1 (tumor necrosis factor (TNF) receptor-associated factor NF-kB activator (TANK) -binding kinase 1), also named as NF-kB-activating kinase (NAK), T2K, is a multimeric kinase that modulates inflammation and autophagy. It is a ubiquitously expressed serine-threonine kinase belonging to the 'noncanonical IkB kinases' (IKKs) recognized for its critical role in regulating type I IFN production. TBK1 is also an important player in autophagy.
Abbreviation
Phospho-TBK1/NAK (Ser172)
UniProt
Q9UHD2
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Phosphorylated human TBK1/NAK (Ser172) peptide
Target
TBK; FTDALS; TBK1; FTDALS4; NAK; T2K
Clonality
Monoclonal,Recombinant
Clone
A843
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IP 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
84 kDa
Observed Molecular Weight
84 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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