Recombinant Phospho-S6 Ribosomal Protein (Ser235, Ser236) Monoclonal Antibody
Product Specifications
Background
Phosphorylation of S6 ribosomal protein correlates with an increase in translation of mRNA transcripts that contain an oligopyrimidine tract in their 5' untranslated regions. These particular mRNA transcripts (5'TOP) encode proteins involved in cell cycle progression, as well as ribosomal proteins and elongation factors necessary for translation. Important S6 ribosomal protein phosphorylation sites include several residues (Ser235, Ser236, Ser240, and Ser244) located within a small, carboxy-terminal region of S6 protein.
Abbreviation
Phospho-S6 Ribosomal Protein (Ser235, Ser236)
UniProt
P62753
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Phosphorylated human S6 Ribosomal Protein (Ser235/236) peptide
Target
RPS; OK/SW-cl; RPS6; S6; OK/SW-cl.2
Clonality
Monoclonal,Recombinant
Clone
A815
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IF 1:100-1:300
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29 kDa
Observed Molecular Weight
32 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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