Recombinant PARP2 Monoclonal Antibody
Product Specifications
Background
PARP2, also named as ADPRT2 and ADPRTL2, is involved in the base excision repair (BER) pathway, by catalyzing the poly (ADPribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. PARP2 initiates the repair of double-strand DNA breaks: recognizes and binds DNA breaks within chromatin and recruits HPF1, licensing serine ADP-ribosylation of target proteins, such as histones, thereby promoting decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand break.
Abbreviation
PARP2
UniProt
Q9UGN5
Host
Rabbit
Reactivity
Human
Immunogen
Peptide. This information is proprietary to PTMab.
Target
ARTD; ADPRT; pADPRT; PARP2; ADPRT2; ADPRTL2; ADPRTL3; ARTD2; PARP-2; pADPRT-2
Clonality
Monoclonal,Recombinant
Clone
A783
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
66 kDa
Observed Molecular Weight
66 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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