Recombinant DNAJC6 Monoclonal Antibody
Product Specifications
Background
DNAJC6, also named AUXILIN, belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. It is a neuronal protein that functions specifically in the pathway of clathrin-mediated endocytosis. It shares homology with GAK, and the two proteins act as cochaperones to support the HSC70 -dependent clathrin uncoating of clathrin-coated vesicles (PMID: 2016009) . DNAJC6 is expressed in various brain regions, including cerebellum, corpus callosum, cortex, striatum, brainstem, pons, putamen, spinal cord and substantia nigra.
Abbreviation
DNAJC6
UniProt
O75061
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Peptide. This information is proprietary to PTMab.
Target
KIAA; DNAJC; KIAA0473; DNAJC6
Clonality
Monoclonal,Recombinant
Clone
A774
Conjugation
Unconjugated
Applications
WB; IHC
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:200-1:400
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
100 kDa
Observed Molecular Weight
115 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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