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Recombinant MEF2C Monoclonal Antibody

Product Specifications

Background

MEF2C is a member of the MEF2 (myocyte enhancer factor 2) family of transcription factors. In mammals, there are four MEF2C-related genes (MEF2A, MEF2B, MEF2C and MEF2D) that encode proteins that exhibit significant amino acid sequence similarity within their DNA binding domains and, to a lesser extent, throughout the rest of the proteins. The MEF2 family members were originally described as muscle specific DNA binding proteins that recognize MEF2 motifs found within the promoters of many muscle-specific genes. Recently, several groups have reported MEF2 binding activity and MEF2 proteins in a wide variety of cell types where these proteins appear to play an important role in growth factor- and stress-induced early gene responses.

Abbreviation

MEF2C

UniProt

Q06413

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Peptide. This information is proprietary to PTMab.

Target

DEL5q; C5DELq; MEF2C; C5DELq14.3; DEL5q14.3; Myocyte-specific enhancer factor 2C; MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C) ; Myocyte enhancer factor 2C; Myocyte specific enhancer factor 2C; OTTHUMP00000222409; Similar to MADS box transcription enhancer factor 2 polypeptide C

Clonality

Monoclonal,Recombinant

Clone

A761

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction; Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells; Cardiovascular

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:5000; IHC 1:500

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

51 kDa

Observed Molecular Weight

55 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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