Recombinant BAF53B Monoclonal Antibody
Product Specifications
Background
BAF53/ACTL6 proteins are highly homologous, actin-related proteins found in the SWI/SNF complex. In addition to the canonical SWI/SNF complex, BAF53A/ACTL6A is also member of the embryonic SWI/SNF complex, known as esBAF, which plays a role in pluripotency and development. BAF53B/ACTL6B is a member of the neural-specific SWI/SNF complex that facilitates binding to target genes and is involved in memory and synaptic plasticity. BAF53/ACTL6 has been shown to interact with c-Myc, where it functions as a cofactor and is important in the transformation process. Further studies have shown ACTL6/BAF53 is associated with EMT and transformation in various cancers.
Abbreviation
BAF53B
UniProt
O94805
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Peptide. This information is proprietary to PTMab.
Target
ACTL; ACTL6; BAF53B; ACTL6B;53 kDa BRG1 associated factor B;53 kDa BRG1-associated factor B; ACL 6B; ACL6B; Actin like 6; Actin like protein 6B; Actin like protein6B; Actin related protein; Actin related protein Baf53b; actin-like 6B; Actin-like protein 6B; Actin-related protein Baf53b; Actl 6; ACTL 6B; ACTL6 B; Arp Na; ArpN a; ArpN alpha; ArpNa; ArpNalpha; Baf 53b; BRG1-associated factor 53B
Clonality
Monoclonal,Recombinant
Clone
A760
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47 kDa
Observed Molecular Weight
47 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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