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Recombinant NCK1 Monoclonal Antibody

Product Specifications

Background

NCK (also known as NCK1 or NCKα) is a broadly expressed oncogenic adapter protein consisting of three SH3 domains and one SH2 domain. NCK1 becomes phosphorylated upon activation of variety of cell surface receptors and is involved in actin cytoskeletal organization induced by many stimuli. NCK2 (also known as NCKβ), a homolog of NCK1, has an overlapping expression pattern and redundant functions with NCK1.

Abbreviation

NCK1

UniProt

P16333

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Peptide. This information is proprietary to PTMab.

Target

NCK adaptor Protein; Cytoplasmic Protein NCK; NCK1; NCK; NCKalpha; nck-1; Cytoplasmic Protein NCK1; NCK adaptor Protein 1; SH2/SH3 Adaptor Protein NCK-Alpha; Melanoma Nck protein; MGC12668; NCK 1; NCK alpha; NCK tyrosine kinase; Non catalytic region of tyrosine kinase; SH2/SH3 adaptor protein NCK alpha

Clonality

Monoclonal,Recombinant

Clone

A741

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

43 kDa

Observed Molecular Weight

50 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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