Recombinant NCK1 Monoclonal Antibody
Product Specifications
Background
NCK (also known as NCK1 or NCKα) is a broadly expressed oncogenic adapter protein consisting of three SH3 domains and one SH2 domain. NCK1 becomes phosphorylated upon activation of variety of cell surface receptors and is involved in actin cytoskeletal organization induced by many stimuli. NCK2 (also known as NCKβ), a homolog of NCK1, has an overlapping expression pattern and redundant functions with NCK1.
Abbreviation
NCK1
UniProt
P16333
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Peptide. This information is proprietary to PTMab.
Target
NCK adaptor Protein; Cytoplasmic Protein NCK; NCK1; NCK; NCKalpha; nck-1; Cytoplasmic Protein NCK1; NCK adaptor Protein 1; SH2/SH3 Adaptor Protein NCK-Alpha; Melanoma Nck protein; MGC12668; NCK 1; NCK alpha; NCK tyrosine kinase; Non catalytic region of tyrosine kinase; SH2/SH3 adaptor protein NCK alpha
Clonality
Monoclonal,Recombinant
Clone
A741
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa
Observed Molecular Weight
50 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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