Recombinant SCP3 Monoclonal Antibody
Product Specifications
Background
SCP3 is an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. SCP3 is required for centromere pairing during meiosis in male germ cells. SCP3 is also required for normal meiosis during spermatogenesis and male fertility. Mutations in SCP3 are associated with azoospermia in males and susceptibility to pregnancy loss in females.
Abbreviation
SCP3
UniProt
Q8IZU3
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Peptide. This information is proprietary to PTMab.
Target
SCP; COR; SYCP; SPGF; RPRGL; SYCP3; COR1; RPRGL4; SCP3; SPGF4
Clonality
Monoclonal,Recombinant
Clone
A719
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa
Observed Molecular Weight
38 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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