Recombinant CLEC2D Monoclonal Antibody

C-type lectin domain family 2 member D (CLEC2D), also known as lectin-like transcript 1 (LLT1) and osteoclast inhibitory lectin (OCIL), is a type II transmembrane C-type lectin receptor primarily expressed upon immune cell activation in T cells, B cells, NK cells, and plasmacytoid and monocyte-derived dendritic cells. CLEC2D interacts with NKR-P1A (KLRB1, CD161) on NK cells and some subsets of T cells, inhibiting NK cell cytotoxicity while alternatively inducing proliferation and IFNγ production in T cells. CLEC2D is also expressed by osteoblasts, inhibiting osteoclast formation and bone resorption.

LLT; CLEC2D; CLAX; LLT1; OCIL; C type lectin related f; C type lectin superfamily 2; CLC2D; CLEC2D protein; Clec2d5; C-type lectin domain family 2 member D; L LT1; Lectin like NK cell receptor; Lectin like transcript 1; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; member D; Osteoclast inhibitory lectin