Recombinant CLEC2D Monoclonal Antibody
Product Specifications
Background
C-type lectin domain family 2 member D (CLEC2D), also known as lectin-like transcript 1 (LLT1) and osteoclast inhibitory lectin (OCIL), is a type II transmembrane C-type lectin receptor primarily expressed upon immune cell activation in T cells, B cells, NK cells, and plasmacytoid and monocyte-derived dendritic cells. CLEC2D interacts with NKR-P1A (KLRB1, CD161) on NK cells and some subsets of T cells, inhibiting NK cell cytotoxicity while alternatively inducing proliferation and IFNγ production in T cells. CLEC2D is also expressed by osteoblasts, inhibiting osteoclast formation and bone resorption.
Abbreviation
CLEC2D
UniProt
Q9UHP7
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CLEC2D fragment
Target
LLT; CLEC2D; CLAX; LLT1; OCIL; C type lectin related f; C type lectin superfamily 2; CLC2D; CLEC2D protein; Clec2d5; C-type lectin domain family 2 member D; L LT1; Lectin like NK cell receptor; Lectin like transcript 1; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; member D; Osteoclast inhibitory lectin
Clonality
Monoclonal,Recombinant
Clone
A686
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
25-35 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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